学位：博士研究生
职称：副教授
研究领域：卫生统计学、生物信息学、流式细胞术
邮箱：kwang_shzu@163.com
通讯地址：石河子大学医学院杏1楼办公室717号
科研学术工作经历与教育背景：
2014.09-至今，石河子大学医学院，预防医学系，副教授
2013.10-2014.08, 生物信息分析公司（墨尔本），生物信息学，数据分析师
2007.01-2013.09，昆士兰大学物理学院数学系，博士后
2006.01-2006.06, 香港城市大学管理科学系，博士后
2005.04-2005.12, 昆士兰大学，物理学院数学系，研究官员
2002.08-2005.03,Curtin大学，副研究员
2000.06-2001.03, 香港城市大学，管理科学系，研究助理
1999.09-2000.02, 科廷大学，公共卫生学院，流行病学与生物统计学系，访问学者
1994.05-2006.09，中国工程物理研究院，工程师
1988.08-1994.04，新疆八一农学院，数学教研室，助教
1999.09-2002.08，科廷大学,公共卫生学院，流行病学与生物统计学系，博士
1990.09-1993.07，北京大学，概率统计系，硕士
1984.09-1988.07，北京大学，数学系，学士
科研项目：
1.兵团创新创业平台与基地建设计划项目：国家血液病临床研究中心分中心（2021CA002），主要完成人，在研。
2.兵团重点领域科技攻关项目：兵团重大突发疫情精准防控决策支持平台研发与示范应用，（2021AB034），主要完成人，在研。
3.国家自然科学基金地区项目：用于急性白血病筛查和免疫分型的八色流式细胞术及其数据分析，（81860374），主持，结题。
4.国家自然科学基金地区项目：新疆哈萨克族代谢综合征及其各因子对心脑血管病危险性预测的队列研究（81560551），主要完成人，结题。
5.Telethon New Children's Hospital Research Fund，Are genome-wide DNA methylation profiles associated with asthma and allergy in children exposed to a 'western' environment? 2013/01-2015/12，主要完成人，结题。
6.Telethon New Children's Hospital Research Fund，Genome-wide DNA methylation profiling in children with acute asthma and HRV-C infection，2013/01 -2014/12，主要完成人，结题。
7.Australian Research Council (ARC)，Joint clustering and matching of multivariate samples across objects，2012/01-2014/12，主要完成人，结题。
8.Griffith Health Institute，Comorbidity and multimorbidity patterns of mental health conditions，2010/01-2010/12，主要完成人，结题。
9.UQ Early Career Researcher (ECR) Grant，The mixture of Skew t-distribution and its application to FACS data，2008/01-2009/12，主持，结题。
10.Australian Research Council（ARC），Mixture models for high-dimensional clustering with applications to brain tumour classification, network intrusion and text classi-fication，2008/01-2010/12，主要完成人，结题。
11.Australian Research Council（ARC），Multivariate methods for the analysis of microarray gene-expression data with applications to cancer diagnostics，2007/01-2011/12，主要完成人，结题。
12.Competitive Earmarked Research Grant (CERG), Research Grants Council of Hong Kong，On the mixing of failure time distributions for non-standard survival data analysis: theory and applications，2004/01-2007/12，主要完成人，结题。
13.WA Health Promotion Foundation，Physical Activity for Sedentary Seniors，2003/01-2005/12，主要完成人，结题。
14.National Health & Medical Research Council (NHMRC) ，Hierarchical finite mixture modelling of health outcomes: a risk-adjusted random effects approach，2003/01-2004/12，主要完成人，结题。
15.City University Strategic Research Grant, Hong Kong，Modeling zero-inflated serial count data with correlated random effects，2002/01-2004/12，主要完成人，结题。
16.Research Grants Council of Hong Kong，Finite mixture survival models with random effects: a GLMM approach，1999/01-2001/12，主要完成人，结题。
学术论文：
1.Wang, Kui*. Clustering of time-course gene expression profiles using normal mixture models with autoregressive random effects,BMC Bioinformatics, 2012,13:300.
2.Wang, Kui*. Multivariate skewt mixture models: applications to fluorescence-activated cell sorting data, DICTA 2009 (Conference of Digital Image Computing: Techniques and Applications, Melbourne), 526-531, 2009.
3.Wang, Kui*. Two-component Poisson mixture regression modelling of count data with bivariate random effects, Mathematical and Computer Modelling, 2007, 46：1468-1476.
4.Wang, Kui*. Multilevel survival modelling of recurrent urinary tract infections, Computer Methods and Programs in Biomedicine, 2007,87(3):225-229.
5.Wang, Kui*. Multilevel logistic regression modelling with correlated random effects: application to the Smoking Cessation for Youth study，Statistics in Medicine, 2006,25(22):3864-3876.
6.Wang, Kui*. Factors influencing hospitalisation of infants for recurrent gastroenteritis in western Australia, Methods of Information in Medicine, 2003,42(3):251-254.
7.Wang, Kui*. A bivariate zero-inflated Poisson regres-sion model to analyze occupational injurie. Accid Anal Prev, 2003,35(4):625-629.
8.Wang, Kui*. A hierarchical Poisson mixture regression model to analyse maternity length of hospital stay, Statistics in Medicine, 2002,21(23):3639-3654.
9.Wang, Kui*. A zero-inflated Poisson mixed model to analyze diagnosis related groups with majority of same-day hospital stays, Computer Methods and Programs in Biomedicine, 2002,68(3):195-203.
10.郭玉娟;等;王奎*.急性髓系白血病流式细胞术全程自动化诊断技术研究，石河子大学学报(自然科学版)，2022,40(4): 17-23.北大中文核心期刊.
11.雷伟,等,王奎*.人工神经网络在流式细胞术数据分析中的应用，医学信息．
12.农卫霞,王奎*. miR-20a-5p表达对胃粘膜相关组织淋巴瘤增殖的影响及其机制研究，石河子大学学报(自然科学版),2021,39(01):102-108.北大中文核心期刊.
13.农卫霞,王奎*,等.miRNA-200a调控淋巴瘤细胞增殖迁移的机制,中国老年学杂志,2020,40(12):2613-2616.
14.农卫霞,王奎*,等.LncRNA MALAT-1对弥漫性大B细胞淋巴瘤增殖和耐药性的影响,中国免疫学杂志,2020,36(14): 1710-1719.
15.Wen Jie Zhang, Feng Li, Lin Tao, Kui Wang*. In Reply: Cervical screening by Pap test and visual inspection enabling same-day biopsy in low-resource, high-risk communities[J].Obstetrics&Gynecology,2019,133(3),584585.
16.孙倩,井明霞,王奎*,宋艳芳.两种常用老年高血压患者服药依从性自我报告问卷适用性分析[J].中国公共卫生杂志,2019.（ISSN：1001-0580）
17.王奎*,芮东升,张眉,等.《卫生统计学》实验课混合式教学改革实践.农垦医学, 2018,40（4）, 369-371.
18.Western environment/lifestyle has increased global genome methylation and decreased global gene expression in chinese immigrants living in australia，Environmental and Molecular Mutagenesis，2016，57：65-73.
19.Association of Insulin Resistance with Glucose and Lipid Metabolism: Ethnic Heterogeneity in Far Western China. Mediators of Inflammation 2016(3):1-8.
20.Association of APOA1 gene polymorphisms (rs670, rs5069, and rs2070665) with dyslipidemia in the Kazakhs of Xinjiang. Genetics and molecular research:GMR 2016,15(2). DOI: 10.4238/gmr.15028094.
21.Prevalence of Hypertension among Adults in Remote Rural Areas of Xinjiang, China. International Journal of Environmental Research and Public Health,2016, 13(6):524. DOI: 10.3390/ijerph13060524.
22.Comparison of Anthropometric and Atherogenic Indices as Screening Tools of Metabolic Syndrome in the Kazakh Adult Population in Xinjiang. International Journal of Environmental Research and Public Health 13(4):428, 2016. DOI: 10.3390/ijerph13040428.
23.Visceral Adiposity and Anthropometric Indicators as Screening Tools of Metabolic Syndrome among Low Income Rural Adults in Xinjiang. Scientific Reports, 2016, 6:36091. doi:10.1038/srep36091.
24.Standardizing Flow Cytometry ImmunophenotypingAnalysis from the Human ImmunoPhenotyping Consortium. Scientific Reports. 6:20686. DOI:10.1038/srep20686.
25.A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes. Cytometry: Part A. 89:16-21. doi:10.1002 /cyto.a.22732.
26.Inference on differential expression using cluster-specific contrasts of mixed effects. Biostatistics 16, 98-112.
27.Lutein alleviates arsenic-induced reproductive toxicityin male mice via Nrf2 signaling. Human & Experimental Toxicology 35(5), 2015. DOI:10.1177/0960327115595682.
28.Association between polymorphisms of fat mass and obesity-associated gene and metabolic syndrome in Kazakh adults of Xinjiang, China. Genetics and molecular research: GMR 14(4):14597-14606, 2015. DOI: 10.4238/2015.November.18.23.
29.Association between Eight Functional Polymorphisms and Haplotypes in the Cholesterol Ester Transfer Protein (CETP) Gene and Dyslipidemia in National Minority Adults in the Far West Region of China. International Journal of Environmental Research and Public Health 12(12):15979-15992, 2015. DOI: 10.3390/ijerph121215036.
30.Association of Inflammation with Metabolic Syndrome among Low-Income Rural Kazakh and Uyghur Adults in Far Western China. Mediators of Inflammation. http://dx.doi.org/10.1155/2015/706768.
31.Joint modeling and registration of cell populations in cohorts of high-dimensional flow cytometric data，PLos One, 2014,9(7):e100334-e100334.
32.Critical assessment of automated flow cytometry data analysis techniques，Nature Methods，2013，10（3）：228-238.
33.Critical assessment of automated flow cytometry data analysis techniques, Nature Methods, 2013,10(3):228-238.
34.Autoantibody profiling to identify biomarkers of key pathogenic pathways in mucinous ovarian cancer，European Journal of Cancer,2010,46(1):170-179.
35.Automated high-dimensional flow cytometric data analysis，Proceedings of the National Academy of Sciences of the United States of America，2009，106（21）：8519-8524.
36.The effectiveness of a physical activity intervention for seniors，American Journal of Health Promotion，2008，22（5）：318-321.
37.Large-scale simultaneous inference with applications to the detection of differential expression with microarray data，Statistica，2008，68：1-30.
38.Contribution to the discussion ofthe paper by F. Chiaromonte and S. Tyekucheva, Test, 2008,17:43-46.
39.Reducing attrition in physical activity programs for older adults, Journal of Aging and Physical Activity, 2007,15(2):152-165.
40.Modelling bivariate count series with excess zeros, Mathematical Biosciences, 2005,196(2):226-237.
41.Recurrent ischemic stroke hospitalisation: A retrospective cohort study using Western Australia linked patient records, European Journal of Epidemiology, 2004,19(11):999-1003.
42.Recurrent gastroenteritis among infants in WesternAustralia: A seven-year hospital-based cohort study, Annals of Epidemiology, 2004,14(2):137-142.
承担教学：承担本科生《医学统计学》《卫生统计学》等课程的教学，留学生《Medical Statis》课程的教学，研究生《医学统计学》、统计软件和R语言及其在公共卫生领域的应用等课程的教学。
