学位:博士研究生
职称:副教授
研究领域:基础医学--病理学与病理生理学(心血管疾病发病机制研究)
邮箱:wangyang_shz@foxmail.com
通讯地址:石河子大学医学院杏4楼办公室208号
学术兼职情况:中国生理学会会员;中国病理生理学会会员
科研学术工作经历与教育背景:
2009.9-2012.6 石河子大学医学院学院基础医学专业,医学硕士学位
2012.9-2015.12 武汉大学基础医学院生理学专业,博士学位
2018.9-2023.8 美国东北俄亥俄医科大学整合医学研究中心,博士后
2012.9-至今 就职于石河子大学医学院基础医学系生理学教研室
2019年获得硕士研究生招生资格
科研项目:
(1)《脂肪源干细胞外泌体促进心肌梗死后心脏功能恢复和心肌血管再生相关机制研究》石河子大学国际科技合作推进计划项目(No:GJHZ202002) 2021.1-2023.12 15万元 主持(校级)
(2)《脂肪源干细胞外泌体中miR-21 通过促血管再生治疗心肌梗死的机制研究》 科技合作计划(No:2022BC006)2022.01-2024.12 94万元 主持(兵团级)
学术论文:(# These authors contributed equally to this article.)
[1] JUGUILON C#, WANG Z#, WANG Y#, et al. Mechanism of the switch from NO to H(2)O(2) in endothelium-dependent vasodilation in diabetes [J]. Basic research in cardiology, 2022, 117(1): 2.
[2] Jamaiyar A, Juguilon C, Wan W, Richardson D, Chinchilla S, Gadd J, Enrick M, Wang T, McCabe C, Wang Y, Kolz C, Clark A, Thodeti S, Ohanyan V, Dong F, Zhou B, Chilian W, Yin L. The essential role for endothelial cell sprouting in coronary collateral growth, J Mol Cell Cardiol. 2022 Jan 22; 165:158-171. PubMed PMID: 35074317.
[3] Winnicki A , Gadd J, Ohanyan V, Hernandez J, Wang Y, Enrick M, McKillen H, Kiedrowski M, Kundu D, Kegecik K, Penn M, Chilian WM, Yin L and Dong F. Role of endothelial CXCR4 in the development of aortic valve stenosis. Front. Cardiovasc. Med. 2022 Sep 6;9:971321. PubMed PMID: 36148060.
[4] ZHU D#, WANG Y#, THOMAS M, et al. Exosomes from adipose-derived stem cells alleviate myocardial infarction via microRNA-31/FIH1/HIF-1α pathway [J]. Journal of molecular and cellular cardiology, 2022, 162: 10-9.
[5] Zhu D, Johnson TK, Wang Y, Thomas M, Huynh K, Yang Q, et al. Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb. Stem Cell Res Ther. 2020;11(1):162.
[6] Johnson TK, Zhao L, Zhu D, Wang Y, Xiao Y, Oguljahan B, et al. Exosomes derived from induced vascular progenitor cells promote angiogenesis in vitro and in an in vivo rat hindlimb ischemia model. Am J Physiol Heart Circ Physiol. 2019;317(4):H765-H76.
[7] Zhang Y#, Wang Y#, Cao WW, Ma KT, Ji W, Han ZW, et al. Spectral Characteristics of Autofluorescence in Renal Tissue and Methods for Reducing Fluorescence Background in Confocal Laser Scanning Microscopy. J Fluoresc. 2018;28(2):561-72.
参加国际学术会议
(Oral/Poster Presentation at National and International Meetings)
Oral/Poster Presentation at National and International Meetings
1. Role of Endothelial CXCR4 on the Development of Aortic Valve Stenosis. Winnicki A, Gadd J, Ohanyan VA, Hernandez G, Wang Y, Enrick M, McKillen H, Kiedrowski M, Kegecik K, Penn MS, Chilian WM, Yin L, Dong F. Circulation. 2022;146:A14024
2. The Regulatory Role of Sirtuin 6 in Diabetic Cardiomyopathy. Wang Y, Enrick M, Gadd J, Juguilon C, Clark A, Kolz C, Chilian WM, Zhang Y and Yin L. Circulation. 2022;146:A15365
3. Role of Sirtuin 6 in Coronary Microvascular Dysfunction. Wang Y, Enrick M, Gadd J, Juguilon C, Clark A, Yin L. The Regulatory Circulation Research. 2022;131:AP3138
4. The Regulatory Role of miR-21 in Heart Failure with Preserved Ejection Fraction (HFpEF). Circulation Research. Juguilon C, Enrick M, Gadd J, Wang Y, Clark A, Kolz C, Ohanyan V, Chilian WM, Yin L. Circulation Research, 2022;131:AP3023
5. The Regulatory Role of miR-21 in Coronary Microcirculation. Juguilon C, Wang Y, Wang Z, Enrick M, Gadd J, Clark A, Chilian W, Yin L. The FASEB Journal. 2022;36.
6. Endothelial Cell Sprouting in Coronary Collateral Growth. Juguilon C, Jamaiyar A, Wan W, Gadd J, Enrick M, Wang Y, Clark A, Chilian WM, Yin L. The FASEB Journal, Volume 36, Issue S1
7. Regulation of the Diabetic Coronary Microcirculation by MicroRNA-21. Juguilon C, Wang Y, Wang Z, Jamaiyar A, Gadd J, Enrick M, Kolz C, Ohanyan V, Chen C, Chen, Y, Chilian W, Yin L. North American Vascular Biology Organization (NAVBO) 2021.
8. The role of Gdf11 in Coronary Collateral Growth. Katherine Yanez, Anurag Jamaiyar, Cody Juguilon, James Gadd, Molly Enrick, Yang Wang, Liya Yin. 2021,The FASEB Journal Volume 35, Issue S1
9. The Diabetic Coronary Microcirculation is Regulated by MicroRNA-21. Cody Juguilon, Anurag Jamaiyar, James Gadd, Yang Wang, Zhiyuan Wang, Molly Enrick, Chris Kolz, Vahagn Ohanyan, Chwen-Lih Chen, Yeong-Renn Chen, William Chilian, Liya Yin. 2021,The FASEB Journal Volume 35, Issue S1
10. The role of CXCR4 in vascular endothelial cells in myocardial ischemia. Yang Wang, Patrick Li, Laura Zhang, Molly Enrick, James Gadd, Cody Juguilon, Feng Dong, Liya Yin, 2021,The FASEB Journal Volume 35, Issue S1
获奖:石河子大学3152中青年骨干教师;全国机能学实验技能大赛二等奖;
专利:医用实验动物血压测定软件V1.0,软件著作权专利,2018年3月
承担教学:承担本科生生理学、人体解剖生理学、机能实验学等课程的教学